Glossary
The state-of-the-art glossary for Waldenström’s macroglobulinemia.
𝛃2 microglobulin
𝛃2 microglobulin in the glossary for Waldenström's macroglobulinemia
Beta-2-microglobulin is a small membrane protein associated with the heavy chains of class I major histocompatibility complex (MHC) proteins and is, therefore, on the surface of all nucleated cells (excludes red blood cells).
Beta-2-microglobulin is a small membrane protein associated with the heavy chains of class I major histocompatibility complex (MHC) proteins and is, therefore, on the surface of all nucleated cells. Levels are elevated in renal dysfunction. Pathologies with high cell turnover, such as hemato-oncological conditions, and rheumatologic diseases are also associated with higher serum β2M levels. 1
Glossary overview